Webcenters globally, investigating the safety and efficacy of Galecto s lead compound, GB0139, in patients with IPF. Initial unblinded data readout is anticipated in 2024. The DSMB informed the company, based on unblinded safety and efficacy data, that there was an imbalance in the serious adverse experiences WebFeb 4, 2024 · May 23, 2024 updated by: Galecto Biotech AB. GALACTIC-1 -A Randomized, Double-blind, Multicentre, Parallel, Placebo-controlled Phase 2b Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF) Investigating the Efficacy and Safety of GB0139, an Inhaled Galectin-3 Inhibitor Administered Via a Dry Powder Inhaler Over 52 Weeks ...
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WebApr 13, 2024 · Galecto has multiple ongoing Phase 2 clinical programs in fibrosis and cancer, including (i) an inhaled galectin-3 modulator (GB0139) in a Phase 2b trial for the treatment of idiopathic pulmonary fibrosis; (ii) an orally active LOXL2 inhibitor (GB2064) in a Phase 2a trial for the treatment of myelofibrosis; (iii) an orally active galectin-3 ... robert half gloucester
Galecto Advances Phase 2b Study of GB0139 in Idiopathic …
WebThe anti-fibrotic effect of GB0139, a small molecule galectin-3 inhibitor, in precision cut lung slices from IPF tissue (ICLAF 2024) - "The reduction in Gal-3 levels was associated with a reduction in markers of fibrosis comparable to that observed with pirfenidone and nintedanib. In IPF PCLuS, GB0139 demonstrates Gal-3 target engagement that ... WebJan 1, 2024 · TD139 (GB0139) Galecto, Inc. (Copenhagen, Denmark) Dry powder inhaler QD • Phase Ia/Ib - safety, tolerability, PK and biomarkers in healthy volunteers and patients with IPF completed (NCT02257177). • Phase IIb - efficacy and safety study (GALACTIC-1, NCT03832946) in IPF patients. GB1211: Galecto, Inc. (Copenhagen, Denmark) Oral … WebMar 15, 2024 · GALACTIC-1 is a 52-week randomized, double-blind, multicenter, parallel, placebo-controlled Phase 2b study being conducted across more than 100 centers globally, investigating the safety and ... robert half global environmental policy